Synergism of spironolactone and lithium in mania.
نویسندگان
چکیده
منابع مشابه
Carbamazepine Lithium Combination for Lithium Resistant Mania
In an open prospective trial five cases of mania identified as lithium non-responders were treated with lithium - carbamazepine conciliation. The prophylactic efficacy of this combination was also studied. The combination proved to be therapeutically and prophylactically effective without significant side effects. The findings and relevant clinical issues are discussed.
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A young manic patient who showed poor response to lithium, neuroleptics and ECT and developed severe cxtrapyramidal side effects restricting the use of neuroleptics in high doses; showed marked clinical improvement with a combination of carbamazepine and lithium with sustained recovery. The case reported to illustrate the possible synergistic action suggested earlier, encouraging the authors to...
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This case indicates that synergism may occur between lithium and spironolactone, which might be clinically useful in patients resistant to lithium or in whom low dose lithium is advisable. Moreover, this case also indicates that spironolactone alone may maintain a manic patient in remission. Further research is needed to assess the mode of action of spironolactone alone or in combination with l...
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how to cite this article: fallah e, arman a, najafi m, shayegh b. effect of tamoxifen and lithium on treatment of acute mania symptoms in children and adolescents. iran j child neurol. spring 2016; 10(2):16-25. abstract objective many studies have supported the role of protein kinase c (pkc) inhibitors in the physiopathology and treatment of bipolar disorder in adults. tamoxifen is one of the d...
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In a 6 month prospective randomized open trial addition of 400 mgs. of carbamazepine per day to lithium carbonate was assessed. Although statistically non-significant, the trends suggest that use of carbamazepine hastens recovery and leads to less frequent use of emergency sedation without any increase in side effects.
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ژورنال
عنوان ژورنال: BMJ
سال: 1986
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.292.6521.661